DPYD Mutations Detection Kit

Real-time
PCR

CE-IVD

-A multiplex real-time PCR that allows amplification of wild-type and mutant nucleic acids.

-Allele Specific Realtime PCR (Aso-Realtime PCR)

-Compatible with FAM and VIC/HEX dual color real-time PCR instruments.

INTENDED USE

The geneMAP™ DPYD Mutations Detection Kit is an Allele Specific Realtime PCR (Aso-Realtime PCR) test designed to detect 5 mutations in DPYD gene in genomic DNA of blood or buccal swab samples.
The kit can detect following mutations in the table.

rs ID	Allelic Variant	Nucleotid Change	Protein Change	Allele Function
rs55886062	*13	c.1679T>G	p.I560S	No Function
rs3918290	*2A	c.1905+1G>A	N/A	No Function
rs67376798	N/A	c.2846A>T	p.D949V	Decreased
rs56038477	HapB3	c.1236G>A	p.E412E	Decreased
rs1801160	*6	c.2194G>A	p.V732I	Decreased