IDH1/2 Mutations Detection Kit

Real-time
PCR

CE-IVD

Detection of 17 mutations in IDH1/2 genes.
Superior analytical sensitivity and specifity with Allele Spesfic PCR.
Fast and Easy use with Multiplex Realtime PCR Technology.

INTENDED USE

The geneMAP™ IDH1/2 Mutations Detection Kit R132L, R132V, R132G, R132S, R132H, R132C, R132P, R100Q, R140G, R140L, R140W, R140Q, R172S, R172K, R172W, R172M, R172G mutations on IDH1/2 genes.

Gene	Exon	Amino Acid Change	Nucleotid Chance	HGSV nt Change
IDH1	4	Wildtype	Wildtype	Wildtype
IDH1	4	R132L	c.395G>T	LRG_610t1:c.395G>T
IDH1	4	R132V	c.394_395 CG>GT	NM_005896.4:c.394_395 delinsGT
IDH1	4	R132G	c.394C>G	LRG_610t1:c.394C>G
IDH1	4	R132S	c.394C>A	LRG_610t1:c.394C>A
IDH1	4	R132H	c.395G>A	LRG_610t1:c.395G>A
IDH1	4	R132C	c.394C>T	LRG_610t1:c.394C>T
IDH1	4	R132P	c.395G>C	LRG_610t1:c.395G>C
IDH1	4	R100Q	c.299G>A	LRG_610t1:c.299G>A
IDH2	4	Wildtype	Wildtype	Wildtype
IDH2	4	R140G	c.418C>G	LRG_611t2:c.418C>G C
IDH2	4	R140L	c.419G>T	LRG_611t2:c.419G>T
IDH2	4	R140W	c.418C>T	LRG_611t2:c.418C>T
IDH2	4	R140Q	c.419G>A	NM_002168.4:c.419G> A
IDH2	4	R172S	c.516G>T	LRG_611t2:c.516G>T
IDH2	4	R172K	c.515G>A	LRG_611t2:c.515G>A
IDH2	4	R172W	c.514A>T	LRG_611t2:c.514A>T
IDH2	4	R172M	c.515G>T	LRG_611t2:c.515G>T
IDH2	4	R172G	c.514A>G	LRG_611t2:c.514A>G