geneMAP™ NPM1 (mutA,B,C&D) Mutation Detection Kit (NPM-RT25)
- Superior Analytical Sensitivity and specificity with Allele Specific PCR
- Fast and Easy to Use with Multiplex Realtime PCR Technology
- Detection of 4 most common mutations on NPM1 gene
- Compatible with FAM and VIC/HEX 2 Colors Real-Time PCR Instruments.
Nucleophosmin-1 (NPM1) mutations represent the most frequent gene alteration in acute myeloid leukemia (AML). The most common NPM1 mutation type, accounting for 75 to 80% of cases, is referred to as mutation A (NPM1-mutA). These NPM1 alterations have been shown to possess prognostic significance because they appear to identify patients who will benefit from chemotherapy. Given the high prevalence and stability of these mutations over the course of disease.
geneMAP™ NPM1 (mutA,B,C&D) Mutation Detection Kit is an allele-specific (ASO)-RT-PCR assay that enables rapid and sensitive detection of NPM1-mutA B C & D.