geneMAP™ HLA-B*27 Detection Kit (B27-RT50)
- Accurate Results with Allele Specific PCR technology
- Compatible with all Realtime PCR instruments capable of melting curve analysis
HLA-B molecules are cell surface proteins that play an important role in immunity. The frequency of the HLA-B27 variant is about 8% in the general Caucasian population, whereas it is found in over 90% of patients suffering from ankylosing spondylitis (AS). The disease, predominantly striking men between the age of 20 and 40 years, is characterized by inflammation of the sacroiliac joint and progressing stiffness of the spine. Due to the high correlation with the disease, HLA-B27 genotyping is suitable for the differential diagnosis of AS. Other subsets of spondyloarthritis are also associated with HLA-B27, although to a lesser degree.
geneMAP™ HLA-B27 Detection Kit It offers a very simple procedure to identify the HLA-B27 gene associated with ankylosing spondylitis. You can easily and quickly identify the HLA-B27 gene as a multiplex PCR.