- geneMAP™ BCR-ABL1 p190(mbcr) Detection Kit (BCR190-RT48)
- geneMAP™ BCR-ABL1 p230(μbcr) Detection Kit (BCR230-RT48)
- geneMAP™ RUNX1-RUNX1T1 t(8;21) Detection Kit (AML1-RT24)
- geneMAP™ TCF3/PBX1 t(1;19) Detection Kit (E2A-RT24)
- geneMAP™ MLL-AF4 t(4;11) Detection Kit (MLL-RT24)
- geneMAP™ TEL-AML1 t(12;21) Detection Kit (TEL-RT24)
- geneMAP™ CBFB-MYH11 Inv(16) Detection Kit (CBF-RT24)
- geneMAP™ PML-RARA t(15;17) bcr1&bcr2, bcr3 Detection Kit (PML-RT24)
- geneMAP™ FIP1L1-PDGFRA Detection Kit (FIP1-RT24)
geneMAP™ BCR-ABL1 p190(mbcr) Detection Kit (BCR190-RT48)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ BCR-ABL1 p230(μbcr) Detection Kit (BCR230-RT48)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ RUNX1-RUNX1T1 t(8;21) Detection Kit (AML1-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ TCF3/PBX1 t(1;19) Detection Kit (E2A-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ MLL-AF4 t(4;11) Detection Kit (MLL-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ TEL-AML1 t(12;21) Detection Kit (TEL-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ CBFB-MYH11 Inv(16) Detection Kit (CBF-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ PML-RARA t(15;17) bcr1&bcr2, bcr3 Detection Kit (PML-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |
geneMAP™ FIP1L1-PDGFRA Detection Kit (FIP1-RT24)
FEATURES
- Superior Analytical Sensitivity (Log4 Reduction)
- Fast and Easy to Use with One Step RT-qPCR Technology
- Accurate Relative Quantitation with Multiplex PCR (Fusion Transcripts/ABL1)
- Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
- CE-IVD
Leukemia is one of the most common cancer types worldwide, presenting 250,000 cases annually. Leukemia is described as a malignant disease caused by abnormal white blood cells produced in bone marrow. An exacerbated and uncontrolled production of abnormal blood cells occurs, leading to a decreased production of healthy blood cells, promoting the rise of bleeding, several infections and severe anemia. In addition, leukemic cells can also spread to other organs such as spleen, brain, lymph nodes and other tissues.
Chromosomal translocations result in creation of gene fusion transcripts that aberrantly modulate various cellular processes. The table below lists translocations that are commonly associated with childhood and adult leukemias.
Translocation | Fusion Gene | Diagnosis | Frequency |
t(8;21)(q22;q22) | AML1-ETO (RUNX1-RUNX1T) | Acute myeloid leukemia (AML) | 8% |
t(1;19)(q23;p13) | TCF3/PBX1 | Childhood precursor-B-ALL Adult precursor-B-ALL | 3-5% 3% |
t(4;11)(q21;q23) | MLL-AF4 | Childhood and adult precursor-B-ALL | 5% |
t(12;21)(p13;q22) | TEL-AML1 | Childhood precursor-B-ALL | 25% |
Inv(16) (p13q22) | CBFB-MYH11 | Acute myeloid leukemia (AML) | 8-9% |
t(15;17)(q22;q21) | PML-RARA bcr1, bcr2, bcr3 | Acute Promyelocytic Leukemia (APL) | 95% |
t(9;22)(q34:q11) | Minor BCR-ABL1 (p190) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 5% (Pediatrics) 5-50%(Adults) |
t(9;22)(q34:q11) | Micro BCR-ABL1 (p230) | Acute Lymphoblastic Leukaemia (ALL) or Chronic Myeloid Leukemia (CML) | 1-3% |
Interstitial 4q12 deletion | FIP1L1-PDGFRA | Eosinophilia associated myeloproliferative disorders |