geneMAP™ FMF 11 Mutation Detection Kit (FMF-RT50)
Mutation Coverage: E148Q, M694V, V726A, M680I (G/C), K695R, R408Q, M694I, R761H, P369S, F479L, A744S
geneMAP™ FMF 5 Mutation Detection Kit (FMF5-RT50)
Mutation Coverage: E148Q, M694V, V726A, M680I (G/C),P369S
- Accurate Results with Allele Specific PCR technology
- Compatible with all Realtime PCR devices capable of melting curve analysis
Familial Mediterranean Fever (FMF) is an autosomal recessive, inflammatory disorder characterized by short, recurrent attacks of fever, accompanied by pain in the abdomen, chest or joints, and erysipelas-like erythema. The most severe complication is progressive amyloidosis, leading to end-stage renal failure. FMF predominantly affects Turks, Arabs, Armenians and Sephardic Jews, with carrier rates reported as high as 1 in 5. FMF has also been observed, in lower frequencies, throughout the Mediterranean area.