geneMAP™ FII Mutation Detection Kit (FII-RT50)

Prothrombin/Factor II, G20210A
Carriers have elevated risk for thrombosis; significantly increased risk in combination with FV Leiden.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

geneMAP™ FV (Leiden) Mutation Detection Kit (FV-RT50)

Factor V Leiden, G1691A/R506Q
One of the most important genetic risk factors for inherited thrombophilia, found in 20-50% of patients with VTE.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

geneMAP™ FXIII Mutation Detection Kit (FXIII-RT50)

Factor XIII (F13A1)
The V34L variant plays a protective role against venous thrombosis. It has also been associated with lower risk for stroke and myocardial infarction.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

geneMAP™ MTHFR677 Mutation Detection Kit (MTHFI-RT50)

MTHFR C677T
Homozygosity increases susceptibility to thrombosis in the presence of additional risk factors.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

geneMAP™ MTHFR1298 Mutation Detection Kit (MTHFII-RT50)

MTHFR, A1298C
Compound heterozygosity for MTHFR C677T and MTHFR A1298C is considered a risk factor for cardiovascular disease.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

geneMAP™ PAI (4G/5G) Mutation Detection Kit (PAI-RT50)

Plasminogen Activator Inhibitor 1 (PAI-1/ SERPINE1) 4G/5G
The 4G allele is considered to be a mild risk factor for VTE and Myocardial Infarction.

FEATURES

  • Easy to Use with Ready to Reaction Mix
  • Accurate Results (Includes Homozygous & Heterozygous Controls)
  • Compatible with FAM and VIC/HEX Dual Color Real-Time PCR Instruments
  • CE-IVD

The genMAPTM Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia

ADVANTAGES

  • Compatible with all Real-Time PCR devices
  • Fast and easy to use
  • READY TO USE REAGENTS

The Genmark Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia;

Factor V Leiden, G1691A/R506Q

One of the most important genetic risk factors for inherited thrombophilia, found in 20-50% of patients with VTE.

Prothrombin/Factor II, G20210A

Carriers have elevated risk for thrombosis; significantly increased risk in combination with FV Leiden

MTHFR C677T Mutasyonu

Homozygosity increases susceptibility to thrombosis in the presence of additional risk factors.

MTHFR, A1298C

Compound heterozygosity for MTHFR C677T and MTHFR A1298C is considered a risk factor for cardiovascular disease.

Plasminogen Activator Inhibitor 1 (PAI-1/ SERPINE1) 4G/5G

The 4G allele is considered to be a mild risk factor for VTE and Myocardial Infarction.

Factor XIII (F13A1)

The V34L variant plays a protective role against venous thrombosis. It has also been associated with lower risk for stroke and myocardial infarction.

ADVANTAGES

  • Compatible with all Real-Time PCR devices
  • Fast and easy to use
  • READY TO USE REAGENTS

The Genmark Thrombophilia assay offers a very simple procedure for testing the most relevant mutations implicated in the risk of an abnormality of blood coagulation, leading to increased risk for thrombosis. Thrombophilia can be identified in 50% of people who have an episode of thrombosis that was not provoked by other causes. Venous thrombosis is one of the most common thrombotic disorders affecting up to 2 in 1000 individuals every year and is associated with life-threatening conditions such as pulmonary embolism.

It is a multiplex RT – PCR reagent kit for simultaneous detection of genetic risk factors associated with thrombophilia;

Factor V Leiden, G1691A/R506Q

One of the most important genetic risk factors for inherited thrombophilia, found in 20-50% of patients with VTE.

Prothrombin/Factor II, G20210A

Carriers have elevated risk for thrombosis; significantly increased risk in combination with FV Leiden

MTHFR C677T Mutasyonu

Homozygosity increases susceptibility to thrombosis in the presence of additional risk factors.

MTHFR, A1298C

Compound heterozygosity for MTHFR C677T and MTHFR A1298C is considered a risk factor for cardiovascular disease.

Plasminogen Activator Inhibitor 1 (PAI-1/ SERPINE1) 4G/5G

The 4G allele is considered to be a mild risk factor for VTE and Myocardial Infarction.

Factor XIII (F13A1)

The V34L variant plays a protective role against venous thrombosis. It has also been associated with lower risk for stroke and myocardial infarction.

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