geneMAP™ MGMT Methylation Analysis Kit (MGM-RT50)
- Superior Analytical Sensitivity and specificity with Methylation Specific PCR
- Fast and Easy to Use with Multiplex Realtime PCR Technology
- Quantitative Methylation Analysis (Calculation of Methylation Level %)
- Compatible with FAM, VIC/HEX two Colors Real-Time PCR Instruments
The MGMT Promoter Methylation Detection Kit is a methylation-specific Realtime PCR (MSP) test designed to detect and quantification O (6) -methylguanine-DNA methyltransferase (MGMT) promoter hypermethylation status in genomic DNA of glioblastoma multiform (GBM) tumors. MGMT promoter methylation has been shown to lead to increased sensitivity to alkylating agents such as temozolomide and to have a favorable prognostic significance.