geneMAP™ JAK2 Exon 12 Mutation Screening Kit (JK12-RT50)

FEATURES

  • Superior Analytical Sensitivity and specificity with Allele Specific PCR
  • Fast and Easy to Use with Multiplex Realtime PCR Technology
  • Screening of 6 most common mutations on exon12 JAK2 gene
  • Compatible with FAM Color Real-Time PCR Instruments (Melting Curve Analysis)
  • CE-IVD

Mutations within exon 12 of the JAK2 gene occur in most cases of JAK2 V617F-mutation negative polycythemia vera. Testing for JAK2 exon 12 mutations may aid in the diagnosis of polycythemia vera and is recommended in patients with JAK2 V617F-negative erythrocytosis. This test will qualitatively detect JAK2 exon 12 mutations in peripheral blood or bone marrow specimens with a sensitivity down to 2% mutant allele. This is a second order test and should be used only following a JAK2 V617F-negative result.

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