geneMAP™ FMF 11 Mutation Detection Kit (FMF-RT50)
Mutation Coverage: E148Q, M694V, V726A, M680I (G/C), K695R, R408Q, M694I, R761H, P369S, F479L, A744S
geneMAP™ FMF 5 Mutation Detection Kit (FMF5-RT50)
Mutation Coverage: E148Q, M694V, V726A, M680I (G/C),P369S
FEATURES
- Accurate Results with Allele Specific PCR technology
- Compatible with all Realtime PCR devices capable of melting curve analysis
- CE-IVD
Familial Mediterranean Fever (FMF) is an autosomal recessive, inflammatory disorder characterized by short, recurrent attacks of fever, accompanied by pain in the abdomen, chest or joints, and erysipelas-like erythema. The most severe complication is progressive amyloidosis, leading to end-stage renal failure. FMF predominantly affects Turks, Arabs, Armenians and Sephardic Jews, with carrier rates reported as high as 1 in 5. FMF has also been observed, in lower frequencies, throughout the Mediterranean area.